Clinical Laboratory Immunology 1st Edition Maahon Tice Test Bank

 978-0130933003

MULTIPLE CHOICE. Choose the one alternative that best completes the statement or answers the question.
1) How are hypersensitivities treated?
A) With antihistamines and epinephrine.
B) By avoiding the antigen.
C) With corticosteroids.
D) With immune system manipulation.
E) All of the above.

2) A positive test for the presence of antibodies in a complement fixation test is
A) precipitation of antigen/antibody complexes.
B) lysis of red blood cells.
C) no lysis of red blood cells.
D) no precipitation of antigen/antibody complexes.

SHORT ANSWER. Write the word or phrase that best completes each statement or answers the question.
3) The causative organism of botulism is particularly virulent because of the ________ it
secretes.

MULTIPLE CHOICE. Choose the one alternative that best completes the statement or answers the question.
4) What advantage does DNA polymerase from Thermus aquaticus (Taq polymerase) have over
DNA polymerase from E. coli?
A) It is more heat stable.
B) DNA gyrase does not have to be added to the mixture to unwind the DNA prior to
synthesis.
C) It synthesizes DNA more accurately with fewer random nucleotide mismatches.
D) It synthesizes DNA more rapidly.

5) When foreign tissue is transplanted, the recipient’s T cells react against
A) public epitopes. B) alloepitopes.
C) private epitopes. D) All of the above.

SHORT ANSWER. Write the word or phrase that best completes each statement or answers the question.
6) The HLA types DR2 and DQ1 are associated with ________.
MULTIPLE CHOICE. Choose the one alternative that best completes the statement or answers the question.
7) Which characteristic(s) below do herpes viruses share?
A) Virtually impossible to grow in artificial cell culture.
B) Poor antibody response to infection and generally insensitive serologic testing.
C) Active infections that become latent, potentially reactivating many years later.
D) Generally only cause clinical symptoms in immunocompromised patients.
E) All of the above.

8) Anemia due to antibody to intrinsic factor would be most associated with which disease?
A) Pernicious anemia
B) Autoimmune hemolytic anemia
C) Systemic lupus erythematosus
D) Paroxysmal nocturnal hemoglobinuria
E) Idiopathic thrombocytopenia purpura

9) Which of the following is (are) TRUE regarding acceptable specimens for HLA typing by
serological methods?
A) Peripheral blood, spleen tissue, and lymph node tissue can all be used for HLA typing.
B) Lithium heparin is the anticoagulant of choice for HLA typing.
C) Specimens preserved in sodium heparin or acid citrate dextrose are acceptable for up to
one week after collection.
D) Specimens should be stored at 2–6° C after collection.
E) All of the above.

10) Which of the type II hypersensitivities listed is caused by spontaneously produced platelet
antibodies?
A) Idiopathic thrombocytopenia purpura B) Hashimoto’s disease
C) Graves’ disease D) Goodpasture’s syndrome

SHORT ANSWER. Write the word or phrase that best completes each statement or answers the question.
11) For HLA typing, the cell of choice is the ________.
12) Explain how viruses are postulated to cause cancer.
MULTIPLE CHOICE. Choose the one alternative that best completes the statement or answers the question.
13) How does the DNA in a pre-B cell differ from germline DNA?
A) The V, D, and J genes have been successfully rearranged on the chromosome coding for
the heavy immunoglobulin chain.
B) The V, D, and J genes have been successfully rearranged on the chromosome coding for
both the heavy and light immunoglobulin chains.
C) The V, D, and J genes have been successfully rearranged on the chromosome coding for
the light immunoglobulin chain.
D) There is no difference in the DNA of these two cells.

SHORT ANSWER. Write the word or phrase that best completes each statement or answers the question.
14) In the skin test for type I hypersensitivities, the reaction is assessed and recorded within
________ minutes.

MULTIPLE CHOICE. Choose the one alternative that best completes the statement or answers the question.
15) Which of the following are components of an antibody? (Check all that apply.)
A) Two identical light chains
B) Two identical heavy chains
C) Carbohydrate
D) Disulfide bonds
E) All of the above

16) Why are whole blood, bone marrow, and bronchoalveolar la